Genestra C1000 100 120 Tablets

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sub Category:
Antioxidants
MPN:
01110-120U
Type of delivery:
Tablet
Ingredient 1:
Vitamin C
Ingredient 2:
Rose Hips
Ingredient 3:
Rutin

Product Overview

Genestra C1000- 120 Tablets

 

• Vitamin C formulation in tablets • 1,000 mg Ascorbic acid per tablet • With added citrus and non-citrus bioflavonoids • Rose hips, hesperidin, quercetin and rutin • Ideal for vegetarians • Convenient tablet format increases patient compliance

C1000 provides vitamin C and a wide range of bioflavonoids to help in the development and maintenance of bones, cartilage, teeth and gums; helps the body to metabolize fats and proteins; helps in wound healing and connective tissue formation; an antioxidant for the maintenance of good health; helps to prevent vitamin C deficiency (1). Product ideal for vegetarians.

 

Additional product info: Aging is accompanied by a variety of physiological, psychological, economic and social changes that compromise nutritional status and/or affect nutritional requirements. For these reasons, the diets of many older adults do not currently meet the recommended intake levels of several essential vitamins and minerals; thus, low micronutrient status is often reported in this population. Nutritional status surveys of the elderly indicate a low to moderate prevalence of frank nutrient deficiencies, but an increased risk of malnutrition, along with evidence of subclinical deficiencies having a direct impact on physiologic function. Overt micronutrient deficiencies have been reported as prevalent in nursing home populations, and recommendations were made that all institutionalized older adults receive a multivitamin/mineral supplement for general nutritional prophylaxis (2).

Oxidative stress plays an important role in the pathogenesis of cardiovascular disease (CVD). Growing evidence suggest that antioxidant vitamins might reduce the risk of disease outcomes by their ability to scavenge free radicals. A case-control study with vitamin E (400 IU/d) and vitamin C (500 mg/d) supplementation in 40 CVD patients for 2 months showed reduced lipid peroxidation and a strengthened antioxidant defense system. Hence, vitamin E and vitamin C supplementation may have beneficial effects on the heart by reducing oxidative stress in CVD patients (3).

Flavonoids are polyphenolic compounds that occur in most foods of plant origin and are significant though minor constituents of the human diet (4). Bioflavonoids which include hesperidin, citrin, rutin, flavones, flavonols, catechin and quercetin were formerly called “Vitamin P”, and were found to be essential components in improving the permeability and integrity of the capillary linings (5). Flavonoids possess antioxidants properties while being able to modulate a number of biological functions such as anti-inflammatory and anti-microbial activities. Limited information from human studies indicates that dietary quercetin supplementation influences blood lipid profiles, glycemic response, and inflammatory status, collectively termed cardiometabolic risks. Randomly assigned subjects were instructed to take either a placebo (n = 43) or 100 mg quercetin capsules each day (n = 49) for 10 weeks. Quercetin-rich supplementation significantly reduced serum concentrations of total cholesterol, LDL-cholesterol and greater HDL-cholesterol. In the quercetin-rich supplementation group, glucose concentrations decreased significantly after 10 weeks supplementation. These results suggest a beneficial role for quercetin as a preventive measure against cardiovascular risk (6). Six weeks' rutin supplementation (500 mg daily) significantly elevated the levels of three plasma flavonoids (quercetin. kaempferol and isorhamnetin) (7).

A double-blind, placebo-controlled, crossover study examined the effect of Hyben Vital, a herbal remedy made from a subtype of Rosa canina which has recently been reported to have anti-inflammatory properties, on the symptoms of osteoarthritis. One hundred and twelve patients with osteoarthritis were randomly allocated to treatment with either Hyben Vital 5 g daily or an identical placebo for 3 months, followed immediately by the alternative treatment. The data of the study indicate that Hyben Vital reduces the symptoms of osteoarthritis (8). In another double-blind placebo-controlled trial, patients with rheumatoid arthritis (RA) according to ARA/ACR criteria were randomised to treatment with encapsulated rose-hip powder 5g daily or matching placebo for 6 months. Health Assessment Questionnaire (HAQ) in the rose-hip group improved whereas in the placebo group it worsened. The Physicians Global Scale demonstrated more improvement in the rose-hip compared to the placebo group. RAQoL and SF-12 physical score improved significantly in the rose-hip group compared to placebo. The results indicate that patients with RA may benefit from additional treatment with rose hip powder (9).

 

Other ingredients: Cellulose, silica, croscarmellose sodium, magnesium stearate, pharmaceutical glaze

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