Product Overview
Genestra Omega 800- 60 softgel capsules
• 525 mg EPA and 275 mg DHA per dose • Helps support cognitive health and/or brain function(1) • Helps maintain/support cardiovascular health(2) • Helps to reduce serum triglycerides/triacylglycerols(3) • Sourced from sardine and anchovy • High triglyceride formula
Omega 800 is naturally flavored with essential oil of orange and does not have a fishy aftertaste. Source of omega-3 fatty acids, EPA and DHA for the maintenance of good health (4).
Additional product info: Fish oils may improve cardiovascular health by altering lipid metabolism, inducing haemodynamic changes, decreasing arrhythmias, modulating platelet function, improving endothelial function and inhibiting inflammatory pathways (3). In fact, fish oil helps support and maintain cardiovascular health and to help reduce serum triglycerides/triacylglycerols (4). Eicosapentaenoic acid (EPA; 22:5n-3) and docosahexaenoic acid (DHA; 22:6n-3) are the 2 principal omega-3 fatty acids in marine oils. Recent data from human studies showed that these 2 fatty acids have differential effects on serum lipids and lipoproteins, serum glucose (4 grams EPA), heart rate (4 grams DHA) and endothelial function (5). EPA and DHA alter membrane fluidity, interact with transcription factors such as PPAR and sterol regulatory element binding protein, and are substrates for enzymes including cyclooxygenase, lipoxygenase and cytochrome P450 (6). Studies also show that EPA and DHA (1.6-2.0 grams EPA and 0.9-1.2 grams DHA) found in fish oils generate bioactive lipid mediators that reduce inflammation and polymorphonuclear leukocyte recruitment in numerous inflammatory disease models (7),(8) . The independent effects of EPA and DHA are however poorly understood. While both EPA and DHA decrease TAG levels, only DHA appears to increase HDL and LDL particle size. Evidence to date also suggests that 2.8-4 grams DHA is more efficient in decreasing blood pressure, heart rate and platelet aggregation compared to EPA (9). EPA (4 gr/day), but not DHA, appears to increase fasting glucose concentrations in overweight, mildly hyperlipidemic men (10). Thus, reduction of postprandial triacylglycerol (TG) concentration may be cardioprotective. Studies have shown that chronic omega-3 fatty acid supplementation (4 grams of either EPA or DHA) significantly lowers postprandial TG concentrations regardless of the type of fat in test meal (11).
Fish oil supplementation providing 150-2,000 mg EPA + DHA, including at least 150 mg DHA per day supports the development of the brain, eyes and nerves in children up to 12 years of age and at 100-3,000 mg EPA + DHA, including at least 100 mg DHA per day helps support cognitive health and brain function (12).
