Product Overview
Pharmax Finest Pure Cod Liver Oil (Orange & Lemon)- 10.1 fl oz (300 ml)
- •355mg EPA and 532mg DHA per serving size
- • Helps support cognitive health and/or brain function (1)
- • Helps support the development of the brain, eyes and nerves in children up to 12 years of age (2)
- • Helps maintain/support cardiovascular health (3)
- • Helps to reduce serum triglycerides/triacylglycerols (4)
- • With added vitamins
- • Includes vitamin A and D
- • Convenient, great-tasting liquid format
- • Essential oils of orange and lemon flavour increases patient compliance
Additional product info:
Cod liver oil is an important source of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). Long-chain n-3 fatty acids are incorporated into cell membranes. Favourable changes of plasma and cellular lipids, blood platelet function and eicosanoid formation were noted in healthy adult male volunteers who consumed 10–40 ml of cod liver oil (9.4% EPA; 13.8% DHA) daily for five months (1). The n-3 polyunsaturated fatty acids from the cod liver oil supplement are rapidly and reversibly incorporated into plasma, platelet and red cell membrane phospholipids, largely at the expense of n-6 polyunsaturated fatty acids (2).
EPA and DHA are crucial to brain development up to 12 years of age and normal brain functioning. DHA is particularly important to brain functioning due to its influence on neural membrane properties, which modulate cell signalling. DHA concentration in the brain decreases with age in humans and this has been postulated to be consequential to the age-related deterioration in central nervous system functions (3. Fish oil supplementation supports the development of the brain, eyes and nerves in children and adolescents and helps support cognitive health and brain function (4). A study suggests that maternal concentration of n-3-long-chain polyunsaturated fatty acids (10 ml Cod liver oil; 1183 mg DHA + 803 mg EPA) during pregnancy might be of importance for later cognitive function of their child, such as sequential processing (5).
The health benefits of vitamin A include the maintenance of eyesight, bone and skin membranes, and to help maintain immune function. Vitamin A also aid in maintaining night vision and development and maintenance of teeth (6).
Vitamin D aid the maintenance of bone, tooth development and maintenance as well as the absorption of calcium and phosphorus (7).
References:
1 von Schacky C, Fischer S, Weber PC. Long-term effects of dietary marine omega-3 fatty acids upon plasma and cellular lipids, platelet function, and eicosanoid formation in humans. J Clin Invest. 1985 Oct;76(4):1626-31. Page 1630, Conclusion
2 Lorenz R, Spengler U, Fischer S, Duhm J, Weber PC. Platelet function, thromboxane formation and blood pressure control during supplementation of the Western diet with cod liver oil. Circulation. 1983 Mar;67(3):504-11. Page 507, Discussion, 2nd paragraph
3 Danthiir V, Burns NR, Nettelbeck T, Wilson C, Wittert G. The Older People, Omega-3, and Cognitive Health (EPOCH) trial design and methodology: A randomised, double-blind, controlled trial investigating the effect of long-chain omega-3 fatty acids on cognitive ageing and wellbeing in cognitively healthy older adults. Nutr J. 2011 Oct 20;10(1):117. Page 2, Background, 2nd paragraph
4 NHPD Monograph on Fish Oil. March 2009.
5 Helland IB, Smith L, Blomén B, Saarem K, Saugstad OD, Drevon CA. Effect of supplementing pregnant and lactating mothers with n-3 very-long-chain fatty acids on children's IQ and body mass index at 7 years of age. Pediatrics. 2008 Aug;122(2):e472-9. Abstract, Conclusion; Page e477, Conclusion
6 NHPD Monograph on Vitamin A. March 2010.
7 NHPD Monograph on Vitamin D. August 2007.
Other ingredients: Essential oils of orange and lemon, natural mixed tocopherols