Stay Ahead of Cold & Flu Season With These Key Nutrients

Stay Ahead of Cold & Flu Season With These Key Nutrients

As we head into winter and spend more time indoors, conditions become ideal for cold and flu season. That’s why it’s essential to give our bodies the nutrients needed to keep the immune system strong. 

Several core nutrients play key roles in supporting immune function, including vitamins C and D, zinc, elderberry, selenium, omega-3 and probiotics. Here’s how each one contributes to a healthy immune response.

 

Vitamin C

While vitamin C doesn’t prevent the common cold, it does help protect the body from free radicals that can weaken immune defenses. Because our bodies can’t produce vitamin C, we must get it from foods like citrus fruits, berries, tomatoes, melons, and many vegetables including peppers, leafy greens, cruciferous vegetables, root vegetables, and winter squash.

Vitamin D

Vitamin D levels often drop at this time of year as sunlight exposure decreases. Still, this is when we need it most. Research shows that adequate vitamin D may help reduce the risk of acute respiratory infections and supports balanced immune function throughout winter.

Zinc

Zinc’s role in immunity became clear in the 1960s when deficiencies were first identified. Since then, research has shown that zinc supports immune cell development, reduces oxidative stress, and serves as a cofactor for enzymes essential for immune responses. 

Elderberry

Black elderberries are naturally rich in antioxidants, especially vitamin C. Emerging evidence suggests elderberry may help reduce the severity and duration of upper-respiratory symptoms, making it a popular seasonal support. 

Selenium

Selenium is an essential mineral that plays a critical role in defending against pathogens. It supports free-radical-fighting enzymes like glutathione peroxidase, promotes healthy immune responses, aids in antibody production, and helps maintain a strong intestinal barrier.

Probiotics

More than 70% of your immune cells reside in the gut, making the microbiome a key player in immunity. Maintaining microbial balance can significantly support immune function, and promising research suggests certain probiotics may reduce the frequency of colds and flu. 

Omega-3 Fatty Acids

Known for their heart and brain benefits, omega-3 fatty acids also support immune health. Some research indicates they may help improve the body’s immune response by promoting balanced inflammation.

While we can’t avoid cold and flu season entirely, we can give our bodies a fighting chance. Eating a nutrient-dense diet and supplementing where needed can help strengthen your defenses and prepare you for the months ahead. 

These statements have not been evaluated by the Food and Drug Administration.


References

Arthur, J.R., and R. C. McKenzie, G.J., Beckett. (2003). The Journal of Nutrition. https://www.sciencedirect.com/science/article/pii/S0022316622158852

Bodur, M., Yilmaz, B., Ağagündüz, D., & Ozogul, Y. (2025). Immunomodulatory Effects of Omega-3 Fatty Acids: Mechanistic Insights and Health Implications. Molecular nutrition & food research, 69(10), e202400752. https://pmc.ncbi.nlm.nih.gov/articles/PMC12087734/

Carr, A. C. & Maggini, S. (2017). Vitamin C and Immune Function. PMC. Nutrients. https://pmc.ncbi.nlm.nih.gov/articles/PMC5707683/?utm_source=chatgpt.com

De Boer, S. (2023). Zinc is good for your immune system: here’s why. Health & Science Magazine. https://www.health-sciencemagazine.com/the-immune-system/zinc-is-good-for-your-immune-system-heres-why

Hemilä, H. (2017). Zinc lozenges and the common cold: a meta-analysis. PMC. The Journal of the Royal Society of Medicine. https://pmc.ncbi.nlm.nih.gov/articles/PMC5418896/?utm_source=chatgpt.com

Hemilä, H., Chalker, E., & Tukiainen, J. (2022). Quantile Treatment Effect of Zinc Lozenges on Common Cold Duration: A Novel Approach to Analyze the Effect of Treatment on Illness Duration. Frontiers in pharmacology, 13, 817522. https://pmc.ncbi.nlm.nih.gov/articles/PMC8844493/?utm_source=chatgpt.com

Hawkins J. et al. Black elderberry (Sambucus nigra) meta-analysis (2019). https://pmc.ncbi.nlm.nih.gov/articles/PMC9400717/

Hoffmann, P. R., & Berry, M. J. (2008). The influence of selenium on immune responses. Molecular nutrition & food research, 52(11), 1273–1280. https://pmc.ncbi.nlm.nih.gov/articles/PMC3723386/

How to Maintain Healthy Vitamin D Levels During Short Winter Days. (2025). https://www.timesnownews.com/health/how-to-maintain-healthy-vitamin-d-levels-during-short-winter-days-article-153123381

How Selenium Supports Immune Health and Disease Prevent. (2025). GrassrootsHealth Nutrient Research Institute. https://www.grassrootshealth.net/blog/selenium-supports-immune-health-and-disease-prevention/

Jolliffe, D. A. et al. (2021). Vitamin D supplementation to prevent acute respiratory infections: a systematic review and meta-analysis of 37 randomized controlled trials. The Lancet Diabetes & Endocrinology. The Lancet

Li, R. et al. (2025). Review: The roles of vitamin C in infectious diseases. (Nutrients/SciDirect) sciencedirect.com

Nour, G. et.al. (2023). Effect of Probiotics on Common Cold, Influenza, and Influenza-Like Illness: Systematic Review and Meta-analysis. Clinical Nutrition. https://journals.lww.com/topicsinclinicalnutrition/abstract/2023/07000/effect_of_probiotics_on_common_cold,_influenza,.3.aspx?context=latestarticles

Restivo, J. (2025). Myths and truths about vitamin C. Harvard Health Publishing. https://www.health.harvard.edu/nutrition/myths-and-truths-about-vitamin-c

Saigal, P. et al. (2020). Does zinc improve symptoms of viral upper respiratory tract infections? Evidence-Based Practice. Evidence Based Practice.  https://journals.lww.com/ebp/citation/2020/01000/does_zinc_improve_symptoms_of_viral_upper.32.aspx

Wang, C-H. et al. (2024). Optimal methods of vitamin D supplementation to prevent acute respiratory infections. Nutrition Journal. https://nutritionj.biomedcentral.com/articles/10.1186/s12937-024-00990-w?utm_source=chatgpt.com

Why the Flu is More Common in Winter: The Science Behind the Surge. (2024). https://samaritanmedicalcare.com/why-the-flu-is-more-common-in-winter-the-science-behind-the-surge/

Wessels, I., Maywald, M., & Rink, L. (2017). Zinc as a Gatekeeper of Immune Function. Nutrients, 9(12), 1286. https://pmc.ncbi.nlm.nih.gov/articles/PMC5748737/

Sadler, R. A., Mallard, B. A., Shandilya, U. K., Hachemi, M. A., & Karrow, N. A. (2024). The Immunomodulatory Effects of Selenium: A Journey from the Environment to the Human Immune System. Nutrients, 16(19), 3324. https://www.mdpi.com/2072-6643/16/19/3324?utm_source=chatgpt.com


Back to blog