Product Overview
Genestra Active Chewable B12- 60 tablets
The body’s natural active form for energy production and metabolism
The ACTIVE vitamin B’s utilize premium source ingredients such as methylcobalamin, Metafolin®, riboflavin-5-phosphate and pyridoxal-5-phosphate. These are in the body’s most preferred active forms, helping to provide support to energy production and metabolic processes. The vitamin B complex consists of vitamin B1 (thiamine), B2 (riboflavin), B3 (niacin and niacinamide), B5 (pantothenic acid), B6 (pyridoxine), B7 (biotin), B9 (folate) and B12 (methylcobalamin). As co-enzymes, the B vitamins play an important role in energy production, helping to metabolize carbohydrates, fats and proteins.1 B vitamins also help in normal growth and development through the formation of red blood cells and tissue formation.2 B vitamins are not generally stored in the body in any appreciable amounts (with the exception of vitamin B12) as they are water-soluble substances – thus the requirement for vitamin B supplementation.
Essential vitamin B12 formula in a natural cherry-flavoured chewable format for convenient patient compliance.
Additional product info: Methylcobalamin
Vitamin B12 is essential for normal metabolism of carbohydrates, fat and protein. As a cofactor for methylmalonyl-CoA mutase enzymes, vitamin B12 helps convert odd chain fatty acids and branched chain amino acids into succinyl-CoA, a common citric acid cycle intermediate.3 Vitamin B12 is also required for nucleic acid (DNA) synthesis, methionine synthesis from cysteine, and normal myelin synthesis in the nervous system.4 Along with vitamin B6 and folic acid, adequate levels of vitamin B12 are required to maintain normal plasma homocysteine levels. Methylcobalamin is a more active form, immediately bioavailable upon absorption (unlike other forms which must be converted first).5
References: 1. Health Canada Monographs: Vitamin B1 (Thiamine) , B2 (Riboflavin), B3 (Niacin and Niacinamide), B5 (Pantothenic acid), B6 (Pyridoxine), B7 (Biotin), B9 (Folate) and B12 (Cyanocobalamin) 2. Health Canada Monographs. 3. Boushey CJ, Beresford SAA, Omenn GS, Motulsky AG. A quantitative assessment of plasma homocysteine asa risk factor for vascular disease - Probable benefits of increasing folic acid intakes. JAMA 1995;274:1049-1057. 4. Curtis D, Sparrow R, Brennan L, Van Der Weyden MB. Elevated serum homocysteine as a predictor for vitamin B12 or folate deficiency. Eur J Haematol 1994; 52:227-232. 5. Rauma AL, Törrönen R, Hänninen O, Mykkänen H. Vitamin B-12 status of long-term adherents of a strict uncooked vegan diet (“living food diet”) is compromised. J Nutr 1995; 125:2511-2515.
